Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554132 | 0.81 | GAA (0.48) | TSHRGAAALDH1A1LMNAMEN1 | |
| SCHEMBL8554342 | 0.81 | NTRK1 (0.51) | GAAALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8555685 | 0.81 | KDM4E (0.46) | TSHRGAAHTTALDH1A1LMNA | |
| SCHEMBL8553162 | 0.78 | GAA (0.45) | TSHRGAAALDH1A1LMNAMEN1 | |
| SCHEMBL8551939 | 0.75 | ALDH1A1 (0.48) | TSHRGAAALDH1A1LMNAMEN1 | |
| SCHEMBL8553146 | 0.74 | NTRK1 (0.54) | TSHRHTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2546236 | 0.73 | GAA (0.68) | TSHRGAAALDH1A1LMNAMEN1 | |
| SCHEMBL19002543 | 0.73 | GAA (0.58) | TSHRGAAHTTALDH1A1LMNA | |
| SCHEMBL13664297 | 0.72 | MAPT (0.46) | GAAHTTALDH1A1LMNAMEN1 | |
| SCHEMBL21357576 | 0.71 | GAA (0.50) | TSHRGAAHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |