Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | NRP1 | O14786 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555685 | 0.82 | KDM4E (0.46) | NTRK1NRP1MEN1KMT2AABCB1 | |
| SCHEMBL8559433 | 0.81 | LRRK2 (0.46) | NTRK1MEN1KMT2AABCB1KDM4E | |
| SCHEMBL8554132 | 0.78 | GAA (0.48) | NTRK1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8551939 | 0.77 | ALDH1A1 (0.48) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL8553146 | 0.76 | NTRK1 (0.54) | NTRK1ABCB1KDM4EALDH1A1MAPT | |
| SCHEMBL8553162 | 0.75 | GAA (0.45) | NTRK1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8550649 | 0.71 | NTRK1 (0.46) | NTRK1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL2546236 | 0.70 | GAA (0.68) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL19002543 | 0.70 | GAA (0.58) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL13664308 | 0.69 | GAA (0.48) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |