Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31401390 | 0.77 | KDM4E (0.46) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7380339 | 0.76 | NOTUM (0.59) | ALDH1A1MEN1KMT2ACYP2C9NOTUM | |
| Hydrochloric Acid SCHEMBL4681351 | 0.75 | NOTUM (0.58) | ALDH1A1MEN1KMT2ACYP2C9NOTUM | |
| SCHEMBL8554143 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1CYP2C9NOTUMPOLB | |
| SCHEMBL8547322 | 0.75 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPK1MAPTHTT | |
| SCHEMBL28087158 | 0.74 | NOTUM (0.56) | SMN1; SMN2ALDH1A1MAPK1MAPTHTT | |
| SCHEMBL4684573 | 0.74 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL613112 | 0.72 | NOTUM (0.81) | SMN1; SMN2ALDH1A1MAPK1MAPTHTT | |
| SCHEMBL4961935 | 0.72 | NOTUM (0.81) | SMN1; SMN2ALDH1A1MAPK1MAPTHTT | |
| SCHEMBL31175186 | 0.71 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1HTTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795893-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1998-08-18 | — | — | US | disclosed |