Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.46 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.46 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380339 | 0.86 | NOTUM (0.59) | ALDH1A1CYP3A4KDM4ECYP2C9NOTUM | |
| Hydrochloric Acid SCHEMBL4681351 | 0.85 | NOTUM (0.58) | ALDH1A1CYP3A4KDM4ECYP2C9NOTUM | |
| SCHEMBL8547322 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL6184503 | 0.76 | LSS (0.55) | L3MBTL1NOTUM | |
| SCHEMBL17888359 | 0.75 | LMNA (0.63) | SMN1; SMN2AKR1C3ALDH1A1GAACYP3A4 | |
| SCHEMBL8554145 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CYP3A4L3MBTL1POLB | |
| SCHEMBL3573771 | 0.75 | SLC6A7 (0.81) | SMN1; SMN2AKR1C3ALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL21987079 | 0.75 | POLB (0.81) | SMN1; SMN2AKR1C3ALDH1A1GAACYP3A4 | |
| SCHEMBL7962391 | 0.75 | POLB (0.81) | SMN1; SMN2AKR1C3ALDH1A1GAACYP3A4 | |
| SCHEMBL7956657 | 0.74 | SMN1; SMN2 (0.67) | SMN1; SMN2AKR1C3ALDH1A1GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795893-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1998-08-18 | — | — | US | disclosed |