Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553729 | 0.80 | SIGMAR1 (0.48) | SIGMAR1EBP | |
| SCHEMBL8556730 | 0.75 | SIGMAR1 (0.60) | SIGMAR1EBP | |
| SCHEMBL12964445 | 0.73 | CYP2D6 (0.44) | SIGMAR1EBPKCNH2IDO1TDO2 | |
| SCHEMBL14112078 | 0.72 | CYP2D6 (0.45) | OPRM1OPRL1KCNH2IDO1TDO2 | |
| SCHEMBL7821093 | 0.70 | KCNH2 (0.41) | SIGMAR1EBPOPRM1OPRL1KCNH2 | |
| SCHEMBL29793198 | 0.67 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL19828185 | 0.67 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL8553726 | 0.66 | SIGMAR1 (0.56) | SIGMAR1EBP | |
| SCHEMBL8556699 | 0.66 | OPRM1 (0.40) | SIGMAR1OPRM1OPRL1 | |
| SCHEMBL14112073 | 0.66 | CYP2D6 (0.46) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649407-B1 | DIMERIC PIPERIDINE, TETRAHYDROPYRIDINE AND PIPERAZINE DERIVATIVES | LUNDBECK & CO AS H (DK) | 1998-08-05 | — | — | EP | claimed |