Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553726 | 0.88 | SIGMAR1 (0.56) | SIGMAR1EBP | |
| SCHEMBL7436502 | 0.80 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL8554266 | 0.80 | SIGMAR1 (0.36) | SIGMAR1EBP | |
| SCHEMBL7821093 | 0.74 | KCNH2 (0.41) | SIGMAR1EBP | |
| SCHEMBL1588028 | 0.73 | SIGMAR1 (0.66) | SIGMAR1 | |
| SCHEMBL7431242 | 0.72 | HTR1A (0.56) | — | |
| SCHEMBL14385756 | 0.72 | KCNH2 (0.52) | SIGMAR1EBP | |
| SCHEMBL8690038 | 0.72 | SIGMAR1 (0.40) | SIGMAR1EBP | |
| SCHEMBL7440266 | 0.72 | HTR1A (0.55) | — | |
| SCHEMBL7428553 | 0.72 | HTR1A (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649407-B1 | DIMERIC PIPERIDINE, TETRAHYDROPYRIDINE AND PIPERAZINE DERIVATIVES | LUNDBECK & CO AS H (DK) | 1998-08-05 | — | — | EP | claimed |