SCHEMBL855431

SCHEMBL855431

O=C1CCC(=O)c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.56
MAOB P27338 2/20 0.56
CYP2A6 P11509 1/20 0.56
CES1 P23141 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CDC25B P30305 2/20 0.50
S100A4 P26447 2/20 0.47
BCHE P06276 2/20 0.47
APAF1 O14727 2/20 0.47
TDP2 O95551 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CES2 O00748 1/20 0.47
TERT O14746 1/20 0.47
NPC1 O15118 1/20 0.47
PLIN1 O60240 1/20 0.47
S1PR4 O95977 1/20 0.47
LMNA P02545 1/20 0.47
PLA2G1B P04054 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29385474 1.00 MAOA (0.56) MAOAMAOBCYP2A6CES1MEN1
Water SCHEMBL460840 0.97 MAOA (0.54) MAOAMAOBCYP2A6CES1MEN1
SCHEMBL31157901 0.84 CES1 (0.62) MAOAMAOBCYP2A6CES1BCHE
Acetic Acid SCHEMBL29684240 0.84 NOTUM (0.52) MAOAMAOBCYP2A6CES1MEN1
SCHEMBL2686810 0.84 CES1 (0.62) MAOAMAOBCYP2A6CES1BCHE
SCHEMBL1268680 0.83 MAOA (0.74) MAOAMAOBCYP2A6CES1BCHE
SCHEMBL29353311 0.83 MAOA (0.74) MAOAMAOBCYP2A6CES1BCHE
SCHEMBL24746 0.83 MAOA (0.74) MAOAMAOBCYP2A6CES1BCHE
SCHEMBL31454252 0.81 MAOA (0.71) MAOAMAOBCYP2A6CES1BCHE
SCHEMBL16552853 0.81 MAOA (0.71) MAOAMAOBCYP2A6CES1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240136561-A1 ELECTRICAL REGENERATION OF ELECTROLYTES PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2024-04-25 US claimed
EP-4292156-A1 ELECTRICAL REGENERATION OF ELECTROLYTES President and Fellows of Harvard College (US) 2023-12-20 EP claimed
CN-116964799-A Electric regeneration of electrolytes 哈佛大学校长及研究员协会 2023-10-27 CN claimed
WO-2022174088-A1 ELECTRICAL REGENERATION OF ELECTROLYTES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-08-18 WO claimed
CN-110254025-B Copper-clad plate production treatment process 江西省航宇新材料股份有限公司 2021-01-15 CN claimed
EP-3097904-B1 DEPIGMENTING AGENTS TO LIGHTEN THE SKIN AFFICHEM (FR) 2019-08-14 EP claimed
US-20180221426-A1 Compositions and Methods for Treating and Removing Seborrheic Keratoses STOECKER WILLIAM VAN DOVER (US) 2018-08-09 US claimed
WO-2018145105-A1 COMPOSITIONS AND METHODS FOR TREATING AND REMOVING SEBORRHEIC KERATOSES STOECKER MD WILLIAM VAN DOVER (US) 2018-08-09 WO claimed
EP-2257515-B1 1,4-NAPHTHOQUINONE DERIVATIVES AND THERAPEUTIC USE THEREOF CENTRE NAT RECH SCIENT (FR) 2017-05-17 EP claimed
WO-2016193220-A1 SKIN PIGMENTATION MODIFIERS TO DARKEN OR LIGHTEN THE SKIN AFFICHEM (FR) 2016-12-08 WO claimed
US-20040234945-A1 Fluorimetric determination of analytes by an intramolecular quencher-fluorophore conjugate ROCHE DIAGNOSTICS GMBH (DE) 2004-11-25 US claimed
WO-2002068056-A2 COMBINATION COMPRISING A 1,4-DIOXONAPHATHALENE COMPOUND AND RIBENOSIDE KS BIOMEDIX HOLDINGS PLC (GB) 2002-09-06 WO claimed
US-6342319-B1 NONAQUEOUS ELECTROLYTE SECONDARY BATTERY, NEGATIVE ELECTRODE OF CARBON KABUSHIKI KAISHA TOSHIBA (JP) 2002-01-29 US claimed
JP-3251582-B2 2002-01-28 JP claimed
EP-0820985-B1 Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 2000-08-30 EP claimed
EP-0570414-B1 NAPHTHOQUINONE DERIVATIVES FOR THE TREATMENT OF CHRONIC INFLAMMATION KS BIOMEDIX LTD (GB) 2000-07-05 EP claimed
US-5854273-A Bisimide compounds ADIR ET COMPAGNIE (FR) 1998-12-29 US claimed
EP-0570414-A1 NAPHTHOQUINONE DERIVATIVES FOR THE TREATMENT OF CHRONIC INFLAMMATION KS BIOMEDIX LTD. (GB) 1993-11-24 EP claimed
WO-1992013532-A2 NAPHTHOQUINONE DERIVATIVES FOR THE TREATMENT OF CHRONIC INFLAMMATION CHAYEN JOSEPH (GB) 1992-08-20 WO claimed
EP-0300218-A1 Use of substituted 1,4-naphthoquinones against nites and fungi BAYER AG (DE) 1989-01-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180221426-A1 Compositions and Methods for Treating and Removing Seborrheic Keratoses CAT, CUTA, GPX1 MAOA 2118/4885MAOB 2041/4885CYP2A6 2477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.