Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554333 | 0.85 | SIGMAR1 (0.45) | DRD2HTR2AGRIN1GRIN2BSIGMAR1 | |
| SCHEMBL7431665 | 0.77 | SIGMAR1 (0.54) | DRD2HTR2AGRIN2BSIGMAR1 | |
| SCHEMBL23508721 | 0.74 | TSHR (0.40) | HTR2ASIGMAR1 | |
| SCHEMBL4214758 | 0.73 | SIGMAR1 (0.62) | DRD2HTR2ASIGMAR1 | |
| SCHEMBL28644317 | 0.71 | OXTR (0.39) | — | |
| SCHEMBL7952645 | 0.70 | SIGMAR1 (0.59) | DRD2HTR2ASIGMAR1 | |
| SCHEMBL7437439 | 0.70 | SIGMAR1 (0.42) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7322033 | 0.68 | SIGMAR1 (0.41) | DRD2HTR2ASIGMAR1 | |
| SCHEMBL236649 | 0.68 | OXTR (0.42) | — | |
| SCHEMBL19852257 | 0.67 | OPRM1 (0.39) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649407-B1 | DIMERIC PIPERIDINE, TETRAHYDROPYRIDINE AND PIPERAZINE DERIVATIVES | LUNDBECK & CO AS H (DK) | 1998-08-05 | — | — | EP | claimed |