Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734932 | 0.80 | KMT2A (0.41) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL8011185 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL7892212 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL5338145 | 0.73 | MEN1 (0.35) | ALDH1A1KMT2AMEN1TDP1POLB | |
| SCHEMBL9251844 | 0.72 | CYP19A1 (0.43) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL852350 | 0.71 | EDNRB (0.33) | ALDH1A1KMT2AMEN1POLBMAPK1 | |
| SCHEMBL7248118 | 0.71 | RAB9A (0.46) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7884961 | 0.71 | MAOB (0.40) | ALDH1A1KMT2AMEN1NOS2MAPT | |
| SCHEMBL2230905 | 0.71 | MAPT (0.48) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL2182063 | 0.71 | KMT2A (0.46) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534443-B1 | 3,6-Disubstituted pyridazine derivatives | MITSUBISHI CHEM CORP (JP) | 1998-12-30 | — | — | EP | disclosed |
| US-5462941-A | 1-(cyclohexylalkylamino)-4-(phenyl, thienyl, or furyl) phthalazines; anti-platelet agglutination agents for treatment or prevention of cerebro- or cardiovascular disorders | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0534443-A1 | 3,6-Disubstituted pyridazine derivatives | Mitsubishi Chemical Corporation (JP) | 1993-03-31 | — | — | EP | disclosed |