Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011185 | 0.80 | ALDH1A1 (0.46) | CYP19A1MEN1KMT2AMAOBLMNA | |
| SCHEMBL2182063 | 0.75 | KMT2A (0.46) | CYP19A1AKT1MEN1KMT2AMAOB | |
| SCHEMBL7884961 | 0.75 | MAOB (0.40) | CYP19A1MEN1KMT2AMAOBMAPT | |
| SCHEMBL7248118 | 0.75 | RAB9A (0.46) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL11411431 | 0.73 | GSTP1 (0.39) | MAOBKDM4EESR1TSHR | |
| SCHEMBL8554351 | 0.72 | ALDH1A1 (0.43) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL11413308 | 0.72 | MIF (0.38) | MEN1KMT2AMAOBLMNAKDM4E | |
| SCHEMBL7892212 | 0.71 | ALDH1A1 (0.41) | MEN1KMT2AMAOBLMNAKDM4E | |
| SCHEMBL5338145 | 0.71 | MEN1 (0.35) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL9257287 | 0.71 | MEN1 (0.37) | MEN1KMT2AMAOBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5462941-A | 1-(cyclohexylalkylamino)-4-(phenyl, thienyl, or furyl) phthalazines; anti-platelet agglutination agents for treatment or prevention of cerebro- or cardiovascular disorders | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0534443-A1 | 3,6-Disubstituted pyridazine derivatives | Mitsubishi Chemical Corporation (JP) | 1993-03-31 | — | — | EP | disclosed |