Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6964728 | 0.99 | ADRA1D (0.40) | PDE4AHTR2CHTR2BSLC6A4HTR2A | |
| SCHEMBL10199778 | 0.97 | PDE4A (0.40) | PDE4AHTR2CHTR2BSLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL6954720 | 0.96 | PDE4A (0.40) | PDE4AHTR2CHTR2BSLC6A4HTR2A | |
| SCHEMBL29301888 | 0.86 | HTR1A (0.43) | PDE4AHTR2CHTR2BSLC6A4HTR2A | |
| SCHEMBL255778 | 0.86 | HTR1A (0.43) | PDE4AHTR2CHTR2BSLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL6969650 | 0.85 | HTR1A (0.42) | PDE4AHTR2CHTR2BSLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL6959004 | 0.85 | HTR1A (0.42) | PDE4AHTR2CHTR2BSLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL6963984 | 0.85 | HTR1A (0.42) | PDE4AHTR2CHTR2BSLC6A4HTR2A | |
| SCHEMBL8960045 | 0.79 | KDM4E (0.49) | HTR2CHTR2BHTR2AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL6971302 | 0.79 | SLC6A2 (0.43) | HTR2CHTR2BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863136-A1 | Derivatives of azetidine and pyrrolidine | Akzo Nobel N.V. (NL) | 1998-09-09 | — | — | EP | disclosed |