Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552587 | 0.86 | SMN1; SMN2 (0.45) | ESR1TSHRLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL4769748 | 0.82 | ESR1 (0.54) | ESR1TSHRLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL10353444 | 0.80 | ESR1 (0.55) | ESR1TSHRLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL7467555 | 0.78 | ESR1 (0.41) | ESR1LMNAMAPK1ESR2CYP2C9 | |
| SCHEMBL8554439 | 0.77 | SMN1; SMN2 (0.49) | ESR1TSHRLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL13290804 | 0.76 | TSHR (0.57) | ESR1TSHRLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL388023 | 0.75 | SMN1; SMN2 (0.60) | ESR1TSHRLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL10884235 | 0.75 | LMNA (0.49) | ESR1TSHRLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL11499291 | 0.74 | SMN1; SMN2 (0.58) | ESR1TSHRLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL7561067 | 0.72 | TSHR (0.55) | ESR1TSHRLMNASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |