Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554442 | 0.86 | ESR1 (0.48) | SMN1; SMN2LMNAESR1TSHRCYP1A2 | |
| SCHEMBL8554439 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAESR1TSHRCYP1A2 | |
| SCHEMBL7464917 | 0.81 | ESR1 (0.39) | ESR1TSHRMAPK1ESR2CA12 | |
| SCHEMBL4769748 | 0.76 | ESR1 (0.54) | SMN1; SMN2LMNAESR1TSHRCYP1A2 | |
| SCHEMBL10353444 | 0.75 | ESR1 (0.55) | SMN1; SMN2LMNAESR1TSHRCYP1A2 | |
| SCHEMBL13290804 | 0.70 | TSHR (0.57) | SMN1; SMN2LMNAESR1TSHRCYP1A2 | |
| SCHEMBL388023 | 0.70 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAESR1TSHRCYP1A2 | |
| SCHEMBL10884235 | 0.70 | LMNA (0.49) | SMN1; SMN2LMNAESR1TSHRCYP1A2 | |
| SCHEMBL8550167 | 0.69 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAESR1TSHRCYP1A2 | |
| SCHEMBL11499291 | 0.69 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAESR1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |