Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552015 | 0.92 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8556190 | 0.89 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8553401 | 0.85 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8552384 | 0.84 | NPY1R (0.39) | L3MBTL1EPHX2 | |
| SCHEMBL8550273 | 0.81 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8557639 | 0.81 | L3MBTL1 (0.38) | L3MBTL1PRMT5EPHX2 | |
| Hydrochloric Acid SCHEMBL8551974 | 0.81 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8552782 | 0.80 | ADAMTS5 (0.43) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8552889 | 0.80 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8552595 | 0.80 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |