Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550973 | 0.74 | GPR119 (0.51) | ALDH1A1 | |
| SCHEMBL8623093 | 0.73 | GPR119 (0.49) | MAPTTHRB | |
| SCHEMBL17271988 | 0.73 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1TSHRLMNA | |
| SCHEMBL337418 | 0.73 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL8550451 | 0.73 | L3MBTL1 (0.47) | KMT2AMEN1 | |
| SCHEMBL31452925 | 0.72 | MEN1 (0.66) | KMT2AMEN1ALDH1A1TSHRLMNA | |
| SCHEMBL9408055 | 0.71 | CHRM1 (0.61) | KMT2AMEN1ALDH1A1TSHRTP53 | |
| SCHEMBL947678 | 0.71 | GPR119 (0.50) | MAPTTHRB | |
| SCHEMBL8554518 | 0.71 | L3MBTL1 (0.47) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6643493 | 0.69 | ALDH1A1 (0.60) | KMT2AMEN1ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |