Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554727 | 1.00 | PARP10 (0.53) | PARP10ALOX5ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8559850 | 0.88 | MEN1 (0.42) | PARP10ALOX5ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8559073 | 0.83 | ACACB (0.41) | ALOX5ADAMTS4ALOX5APMAPT | |
| SCHEMBL8559093 | 0.83 | ACACB (0.41) | ALOX5ADAMTS4ALOX5APMAPT | |
| SCHEMBL8555948 | 0.82 | KCNH2 (0.43) | ALOX5 | |
| SCHEMBL8555939 | 0.82 | KCNH2 (0.43) | ALOX5 | |
| SCHEMBL8557021 | 0.82 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL8555246 | 0.81 | GPBAR1 (0.61) | ALOX5 | |
| SCHEMBL8554925 | 0.81 | GPBAR1 (0.61) | ALOX5 | |
| SCHEMBL8555687 | 0.80 | GPBAR1 (0.60) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | claimed |
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |