Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555939 | 0.89 | KCNH2 (0.43) | KCNH2ALOX5MRGPRX4HDAC6 | |
| SCHEMBL8555948 | 0.89 | KCNH2 (0.43) | KCNH2ALOX5MRGPRX4HDAC6 | |
| SCHEMBL8554711 | 0.88 | PARP10 (0.53) | PARP10ALOX5MAOBKDM4EALDH1A1 | |
| SCHEMBL8554727 | 0.88 | PARP10 (0.53) | PARP10ALOX5MAOBKDM4EALDH1A1 | |
| SCHEMBL8557228 | 0.83 | ALOX5 (0.46) | MEN1KMT2AALOX5KDM4EALDH1A1 | |
| SCHEMBL8555246 | 0.79 | GPBAR1 (0.61) | ALOX5FFAR1HDAC6 | |
| SCHEMBL8554925 | 0.79 | GPBAR1 (0.61) | ALOX5FFAR1HDAC6 | |
| SCHEMBL8555687 | 0.78 | GPBAR1 (0.60) | ALOX5FFAR1HDAC6 | |
| SCHEMBL8555104 | 0.78 | GPBAR1 (0.60) | ALOX5FFAR1HDAC6 | |
| SCHEMBL8557021 | 0.78 | ALOX5 (0.52) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |