Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 16/20 | 0.69 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559830 | 0.88 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL8559081 | 0.84 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL8555945 | 0.83 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL8555241 | 0.82 | ALOX5 (0.72) | ALOX5 | |
| SCHEMBL8555093 | 0.81 | ALOX5 (0.71) | ALOX5 | |
| SCHEMBL8557217 | 0.81 | ALOX5 (0.60) | ALOX5 | |
| SCHEMBL8890119 | 0.81 | ALOX5 (0.57) | ALOX5PARP10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8557151 | 0.78 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL8556881 | 0.76 | ALOX5 (0.72) | ALOX5 | |
| SCHEMBL8559593 | 0.76 | ALOX5 (0.72) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | claimed |
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |