Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556881 | 0.90 | ALOX5 (0.72) | ALOX5 | |
| SCHEMBL8559830 | 0.85 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL8554718 | 0.81 | ALOX5 (0.69) | ALOX5 | |
| SCHEMBL8626723 | 0.80 | ALOX5 (0.72) | ALOX5MAPT | |
| SCHEMBL8622657 | 0.79 | ALOX5 (0.71) | ALOX5MAPT | |
| SCHEMBL8557228 | 0.79 | ALOX5 (0.46) | ALOX5MAPTADORA3 | |
| SCHEMBL8649482 | 0.78 | MAPT (0.47) | ALOX5MAPTADORA3 | |
| SCHEMBL8555945 | 0.76 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL8557151 | 0.76 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL8555241 | 0.73 | ALOX5 (0.72) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |