Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | CBX7 | O95931 | 1/20 | 0.45 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.45 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.45 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556616 | 0.82 | TSHR (0.65) | TSHRL3MBTL1DRD4USP2GRM5 | |
| SCHEMBL8554874 | 0.80 | USP2 (0.63) | TSHRL3MBTL1DRD4USP2GRM5 | |
| SCHEMBL31667554 | 0.78 | L3MBTL1 (0.70) | TSHRL3MBTL1DRD4USP2KMT2A | |
| SCHEMBL4506469 | 0.74 | ALDH1A1 (0.69) | TSHRL3MBTL1DRD4USP2KMT2A | |
| SCHEMBL8554715 | 0.74 | L3MBTL1 (1.00) | TSHRL3MBTL1DRD4KMT2AMEN1 | |
| SCHEMBL8553880 | 0.73 | L3MBTL1 (0.64) | TSHRL3MBTL1DRD4USP2KMT2A | |
| SCHEMBL18497019 | 0.71 | BRD4 (0.58) | TSHRL3MBTL1DRD4KMT2AMEN1 | |
| SCHEMBL3660420 | 0.71 | BRD4 (0.58) | TSHRL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL8554042 | 0.71 | L3MBTL1 (0.70) | TSHRL3MBTL1USP2KMT2AMEN1 | |
| SCHEMBL474614 | 0.70 | TSHR (0.60) | TSHRL3MBTL1USP2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |