Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218536 | 1.00 | MAPT (0.56) | MAPTSMN1; SMN2TP53THRBNPC1 | |
| SCHEMBL5831652 | 0.93 | ALDH1A1 (0.54) | MAPTSMN1; SMN2TP53THRBNPC1 | |
| SCHEMBL8554845 | 0.92 | APP (0.51) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL5946763 | 0.92 | APP (0.51) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8553099 | 0.92 | APP (0.51) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8551625 | 0.91 | APP (0.50) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8428720 | 0.90 | NPC1 (0.56) | MAPTSMN1; SMN2TP53THRBNPC1 | |
| SCHEMBL5946928 | 0.88 | CASP3 (0.46) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL11335376 | 0.87 | APP (0.63) | MAPTSMN1; SMN2TP53THRBNPC1 | |
| SCHEMBL8371612 | 0.86 | RARB (0.61) | MAPTSMN1; SMN2NPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440061-B1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KK (JP) | 1998-04-01 | — | — | EP | disclosed |
| US-5284599-A | Benzothiazole with alkyl group having asymmetric carbon connected to halogen; improved response | CANON KABUSHIKI KAISHA (JP) | 1994-02-08 | — | — | US | disclosed |
| US-5236619-A | Benzothiazoles | CANON KABUSHIKI KAISHA (JP) | 1993-08-17 | — | — | US | disclosed |
| EP-0440061-A1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KABUSHIKI KAISHA (JP) | 1991-08-07 | — | — | EP | disclosed |