SCHEMBL8551625

SCHEMBL8551625

CCCCCCc1ccc2nc(-c3ccc(CCCC)cc3)sc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 0.50
KDM4E B2RXH2 4/20 0.49
RAB9A P51151 4/20 0.49
NPC1 O15118 3/20 0.49
GAA P10253 3/20 0.49
MAPT P10636 3/20 0.49
GLA P06280 2/20 0.49
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
SNCA P37840 1/20 0.47
CASP3 P42574 7/20 0.46
SENP8 Q96LD8 7/20 0.46
SENP7 Q9BQF6 7/20 0.46
SENP6 Q9GZR1 7/20 0.46
PCSK9 Q8NBP7 1/20 0.46
RARB P10826 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8553099 0.99 APP (0.51) APPKDM4ERAB9ANPC1GAA
SCHEMBL8554845 0.99 APP (0.51) APPKDM4ERAB9ANPC1GAA
SCHEMBL5946763 0.99 APP (0.51) APPKDM4ERAB9ANPC1GAA
SCHEMBL5946928 0.91 CASP3 (0.46) APPKDM4ERAB9ANPC1GAA
SCHEMBL11335376 0.91 APP (0.63) APPKDM4ERAB9ANPC1GAA
SCHEMBL8554888 0.91 MAPT (0.56) APPKDM4ERAB9ANPC1GAA
SCHEMBL8218536 0.91 MAPT (0.56) APPKDM4ERAB9ANPC1GAA
SCHEMBL8551451 0.89 RARB (0.56) APPKDM4ERAB9ANPC1GAA
SCHEMBL5946699 0.89 APP (0.45) APPKDM4ERAB9ANPC1GAA
SCHEMBL8557251 0.87 ATP4A (0.56) APPKDM4ERAB9ANPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0440061-B1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KK (JP) 1998-04-01 EP disclosed
US-5284599-A Benzothiazole with alkyl group having asymmetric carbon connected to halogen; improved response CANON KABUSHIKI KAISHA (JP) 1994-02-08 US disclosed
US-5236619-A Benzothiazoles CANON KABUSHIKI KAISHA (JP) 1993-08-17 US disclosed
EP-0440061-A1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KABUSHIKI KAISHA (JP) 1991-08-07 EP disclosed