Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556176 | 0.88 | MEN1 (0.42) | PPARGALDH1A1PPARAMAPK1KMT2A | |
| SCHEMBL7422734 | 0.77 | KDM4E (0.44) | PPARGTDP1KDM4EPSMD14RECQL | |
| SCHEMBL8558625 | 0.74 | MEN1 (0.38) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8555826 | 0.70 | KMT2A (0.44) | PPARGKDM4EALDH1A1TP53KMT2A | |
| SCHEMBL7710517 | 0.69 | PPARG (0.38) | PPARGPPARAKMT2AMEN1ATM | |
| SCHEMBL7424222 | 0.67 | HSD17B10 (0.43) | TDP1KDM4EPSMD14RECQLRXFP1 | |
| SCHEMBL27483791 | 0.65 | KDM4E (0.46) | PPARGTDP1KDM4EPSMD14RECQL | |
| SCHEMBL8558633 | 0.65 | ALOX5 (0.40) | ALDH1A1MAPT | |
| SCHEMBL7422800 | 0.65 | KMT2A (0.58) | KDM4EALDH1A1KMT2AMEN1ATM | |
| SCHEMBL7461274 | 0.64 | KDM4E (0.42) | PPARGTDP1KDM4EPSMD14RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |