Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL6310488 | 0.91 | PTGS2 (0.44) | PTGS2PTGS1KDM4EALDH1A1RAB9A | |
| SCHEMBL8555079 | 0.88 | PTGS2 (0.65) | PTGS2PTGS1CA9KMT2AMAPK13 | |
| Methane SCHEMBL6308775 | 0.82 | PTGS2 (0.49) | PTGS2PTGS1KDM4EALDH1A1RAB9A | |
| Methane SCHEMBL6315825 | 0.82 | PTGS2 (0.44) | PTGS2PTGS1KDM4EALDH1A1RAB9A | |
| Methane SCHEMBL6307587 | 0.82 | PTGS2 (0.48) | PTGS2PTGS1KDM4EALDH1A1KMT2A | |
| SCHEMBL8560340 | 0.80 | RXRA (0.46) | PTGS2PTGS1KDM4EALDH1A1RAB9A | |
| SCHEMBL8552519 | 0.79 | PTGS2 (0.76) | PTGS2PTGS1CA2CA9KMT2A | |
| SCHEMBL7504621 | 0.79 | PTGS2 (0.76) | PTGS2PTGS1CA2CA9KMT2A | |
| SCHEMBL5694182 | 0.79 | PTGS2 (0.56) | PTGS2PTGS1CA2CA9KMT2A | |
| SCHEMBL7221357 | 0.78 | F10 (0.40) | PTGS2PTGS1KDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |