Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555744 | 0.88 | HPGDS (0.43) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8556271 | 0.82 | NPC1 (0.47) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8553264 | 0.80 | CYP3A4 (0.38) | NPC1RAB9ASMN1; SMN2GRIA2CYP3A4 | |
| SCHEMBL8553142 | 0.79 | RAB9A (0.55) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8552877 | 0.78 | KDM4E (0.48) | RAB9AGRIA2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8556156 | 0.78 | CYP3A4 (0.40) | GRIA2CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL8552673 | 0.78 | CYP3A4 (0.40) | GRIA2CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL8554697 | 0.78 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2HDAC8GRIA2 | |
| SCHEMBL8552658 | 0.78 | KDM4E (0.56) | NPC1RAB9ASMN1; SMN2GRIA2CYP3A4 | |
| SCHEMBL8551722 | 0.75 | FYN (0.40) | NPC1RAB9ASMN1; SMN2CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546338-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5385692-A | Improved response | CANON KABUSHIKI KAISHA (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0546338-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1993-06-16 | — | — | EP | disclosed |