Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553264 | 0.86 | CYP3A4 (0.38) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL8551722 | 0.85 | FYN (0.40) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL8542748 | 0.85 | FYN (0.40) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL8553142 | 0.85 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL8552877 | 0.84 | KDM4E (0.48) | RAB9AMAPTCYP3A4GRIA2CYP2D6 | |
| SCHEMBL8556156 | 0.83 | CYP3A4 (0.40) | MAPTFYNCYP3A4CYP2C8S1PR3 | |
| SCHEMBL8552673 | 0.83 | CYP3A4 (0.40) | MAPTFYNCYP3A4CYP2C8S1PR3 | |
| SCHEMBL8555744 | 0.83 | HPGDS (0.43) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL8552658 | 0.83 | KDM4E (0.56) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL8555083 | 0.82 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546338-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5385692-A | Improved response | CANON KABUSHIKI KAISHA (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0546338-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1993-06-16 | — | — | EP | disclosed |