Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 11/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26288606 | 0.86 | ALDH1A1 (0.31) | — | |
| SCHEMBL8557719 | 0.78 | CHRM1 (0.34) | CHRM1CHRM3ITGB3ITGA2BLMNA | |
| SCHEMBL310513 | 0.78 | CHRM1 (0.38) | CHRM1CHRM3ITGB3ITGA2BLMNA | |
| Hydrochloric Acid SCHEMBL310124 | 0.76 | GNAO1 (0.38) | CHRM1CHRM3ITGB3ITGA2BLMNA | |
| SCHEMBL24008966 | 0.74 | CHRM1 (0.36) | CHRM1CHRM3ITGB3ITGA2BLMNA | |
| SCHEMBL2169002 | 0.74 | GABRA5 (0.46) | CHRM1CHRM3ITGB3ITGA2BLMNA | |
| SCHEMBL230908 | 0.74 | CHRM1 (0.38) | CHRM1CHRM3ITGB3ITGA2BLMNA | |
| SCHEMBL6750241 | 0.73 | ITGB3 (0.36) | CHRM1CHRM3ITGB3ITGA2BLMNA | |
| Hydrochloric Acid SCHEMBL20775305 | 0.72 | CHRM1 (0.37) | CHRM1CHRM3ITGB3ITGA2BLMNA | |
| Hydrochloric Acid SCHEMBL29891111 | 0.72 | GABRA5 (0.45) | CHRM1CHRM3ITGB3ITGA2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |