Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 14/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 14/20 | 0.52 |
| ▸ | NOS3 | P29474 | 3/20 | 0.49 |
| ▸ | NOS1 | P29475 | 3/20 | 0.49 |
| ▸ | NOS2 | P35228 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651617 | 1.00 | TAS1R3 (0.52) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL6475208 | 0.88 | TAS1R3 (0.53) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL4435078 | 0.88 | TAS1R3 (0.53) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL8556435 | 0.87 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL8556439 | 0.87 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL8557083 | 0.86 | GAA (0.46) | ALDH1A1 | |
| SCHEMBL8656928 | 0.86 | GAA (0.46) | ALDH1A1 | |
| SCHEMBL8556625 | 0.84 | ALDH1A1 (0.51) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL8657346 | 0.84 | ALDH1A1 (0.51) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL8555850 | 0.82 | NOS3 (0.52) | TAS1R3TAS1R1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1080719-C | Substituted 1H-3-aryl-pyrrolidine-2,4-diones derivative | BAYER GMBH (DE) | 2002-03-13 | — | — | CN | disclosed |
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0668267-B1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1998-04-08 | — | — | EP | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| CN-1110680-A | Substituted 1H-3-aryl-pyrrolidine-2,4-diones derivative | BYLL GMBH (DE) | 1995-10-25 | — | — | CN | disclosed |
| EP-0668267-A1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |