Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 9/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.53 |
| ▸ | CLPP | Q16740 | 2/20 | 0.50 |
| ▸ | NOS3 | P29474 | 3/20 | 0.49 |
| ▸ | NOS1 | P29475 | 3/20 | 0.49 |
| ▸ | NOS2 | P35228 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435078 | 1.00 | TAS1R3 (0.53) | TAS1R3TAS1R1CLPPNOS3NOS1 | |
| SCHEMBL4435087 | 0.90 | PRSS1 (0.51) | CLPPMEN1ALDH1A1THRBHTT | |
| SCHEMBL4435085 | 0.90 | PRSS1 (0.51) | CLPPMEN1ALDH1A1THRBHTT | |
| SCHEMBL8651617 | 0.88 | TAS1R3 (0.52) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL8555232 | 0.88 | TAS1R3 (0.52) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL7964610 | 0.86 | TAS1R3 (0.54) | TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL6994293 | 0.86 | TAS1R3 (0.54) | TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL4432499 | 0.86 | PTGS2 (0.50) | MEN1ALDH1A1THRBHTTKMT2A | |
| SCHEMBL6481400 | 0.86 | PTGS2 (0.50) | MEN1ALDH1A1THRBHTTKMT2A | |
| SCHEMBL4421052 | 0.84 | ALDH1A1 (0.52) | TAS1R3TAS1R1MEN1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939888-B2 | 1-H-3-arylpirrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-09-06 | — | — | US | disclosed |
| US-20040019061-A1 | 1-H-3-arylpirrolidine-2,4-dione derivatives | FISCHER REINER (DE) | 2004-01-29 | — | — | US | disclosed |
| US-6472419-B1 | 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives as pest-control agents | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019061-A1 | 1-H-3-arylpirrolidine-2,4-dione derivatives | PRXL2A, DDT, CYP4B1 | TAS1R3 1447/4885TAS1R1 1668/4885CLPP 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.