Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555993 | 0.87 | HPGD (0.46) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL8553642 | 0.85 | AR (0.46) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL8558890 | 0.85 | CCR2 (0.41) | MAPTNPC1KMT2AALDH1A1 | |
| SCHEMBL8557266 | 0.85 | AR (0.51) | MAPTKDM4EHPGDMEN1KMT2A | |
| SCHEMBL8556135 | 0.83 | MAPT (0.48) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL8557997 | 0.83 | AR (0.51) | MAPTNPC1RAB9AHPGDMEN1 | |
| SCHEMBL8559014 | 0.82 | MAPT (0.48) | MAPTRAB9ALMNATP53TSHR | |
| SCHEMBL8560966 | 0.80 | AR (0.48) | MAPTMEN1KMT2ANPSR1SLC40A1 | |
| SCHEMBL9025133 | 0.80 | AR (0.46) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL8556035 | 0.79 | MEN1 (0.45) | HPGDMEN1KMT2ATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |