Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555703 | 0.84 | ADRB3 (0.47) | ADRB3ADRB1FAAHMKNK1MKNK2 | |
| SCHEMBL8109544 | 0.83 | SMN1; SMN2 (0.44) | ADRB3ADRB1SMN1; SMN2SLC6A4KCNA5 | |
| SCHEMBL8550969 | 0.82 | EPHX1 (0.46) | ADRB3ADRB1SMN1; SMN2KCNA5 | |
| SCHEMBL8554047 | 0.81 | SLC6A2 (0.51) | SMN1; SMN2SLC6A4KCNA5CYP11B1CYP11B2 | |
| SCHEMBL8118264 | 0.80 | DGAT2 (0.39) | AKR1C3AKR1C2ADRB3ADRB1KCNA5 | |
| SCHEMBL8117056 | 0.79 | CYP3A4 (0.40) | AKR1C3AKR1C2ADRB3ADRB1KCNA5 | |
| SCHEMBL8552624 | 0.78 | CYP19A1 (0.47) | ADRB3ADRB1SMN1; SMN2MKNK1MKNK2 | |
| SCHEMBL8119038 | 0.77 | CYP11B1 (0.43) | ADRB3ADRB1CYP11B1CYP11B2 | |
| SCHEMBL8555652 | 0.77 | PPARG (0.41) | AKR1C3AKR1C2SMN1; SMN2KCNA5CYP11B1 | |
| SCHEMBL8552459 | 0.77 | CYP17A1 (0.44) | ADRB3ADRB1CYP11B1CYP11B2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |