Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 16/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 16/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 16/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6194063 | 0.85 | CACNA1F (0.41) | ADRA1DADRA1AADRA1BCACNA1FCACNA1D | |
| SCHEMBL6198371 | 0.82 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BCACNA1FCACNA1D | |
| SCHEMBL6195392 | 0.77 | CACNA1F (0.40) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3988068 | 0.77 | MGLL (0.41) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6199441 | 0.75 | MEN1 (0.44) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6262192 | 0.75 | ADRA1D (0.50) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6646229 | 0.75 | ADRA1D (0.39) | ADRA1DADRA1AADRA1BCACNA1FCACNA1D | |
| SCHEMBL6784838 | 0.74 | ADRA1A (0.39) | ADRA1DADRA1AADRA1BCACNA1FCACNA1D | |
| SCHEMBL6247829 | 0.74 | CACNA1F (0.36) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6198367 | 0.72 | ADRA1D (0.41) | ADRA1DADRA1AADRA1BCACNA1FCACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790826-A4 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0790826-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-08-27 | — | — | EP | disclosed |