Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | CCR2 | P41597 | 3/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871803 | 0.95 | HTR1A (0.58) | HTR1AADRA1D | |
| SCHEMBL8870158 | 0.92 | HTR7 (0.55) | HTR1A | |
| SCHEMBL27431034 | 0.91 | HTR1A (0.57) | HTR1A | |
| SCHEMBL8553950 | 0.90 | ADRA2A (0.61) | HTR1AADRA1D | |
| SCHEMBL8553791 | 0.90 | HTR1A (0.59) | HTR1ACCR2ADRA1D | |
| SCHEMBL8556222 | 0.88 | HTR7 (0.62) | HTR1AADRA1D | |
| SCHEMBL8555410 | 0.88 | HTR1A (0.52) | HTR1AADRA1D | |
| SCHEMBL8871079 | 0.87 | HTR1A (0.63) | HTR1ACCR2ADRA1D | |
| SCHEMBL8554898 | 0.87 | HTR1A (0.63) | HTR1ACCR2ADRA1D | |
| SCHEMBL8871176 | 0.86 | HTR1A (0.56) | HTR1AGPR84ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683166-B1 | 3-Indolylpiperidines | MERCK PATENT GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |