Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556135 | 0.85 | MAPT (0.48) | NPC1ALDH1A1RXFP1KDM4ELMNA | |
| SCHEMBL8558438 | 0.85 | HPGD (0.41) | ALDH1A1KDM4ELMNAHSD17B10KMT2A | |
| SCHEMBL8561913 | 0.83 | AR (0.46) | NPC1ALDH1A1RXFP1KDM4ELMNA | |
| SCHEMBL8558890 | 0.83 | CCR2 (0.41) | CCR2VDRCCR1APEX1ACLY | |
| SCHEMBL8554235 | 0.83 | MEN1 (0.45) | KMT2A | |
| SCHEMBL9026048 | 0.81 | MEN1 (0.50) | KMT2A | |
| SCHEMBL8555123 | 0.81 | AR (0.51) | NPC1RXFP1KDM4EKMT2A | |
| SCHEMBL8558557 | 0.81 | MEN1 (0.48) | VDRACLYNPC1ALDH1A1KMT2A | |
| SCHEMBL8557604 | 0.79 | AR (0.51) | ALDH1A1RXFP1KDM4EKMT2A | |
| SCHEMBL9026868 | 0.79 | MAPT (0.42) | RXFP1KDM4ELMNAHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |