Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.39 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026048 | 0.95 | MEN1 (0.50) | MEN1KMT2AARNR4A2BCL2L1 | |
| SCHEMBL8561913 | 0.90 | AR (0.46) | MEN1KMT2AARBCL2L1MCL1 | |
| SCHEMBL8558557 | 0.89 | MEN1 (0.48) | MEN1KMT2ANR4A2BCL2L1MCL1 | |
| SCHEMBL8557604 | 0.87 | AR (0.51) | MEN1KMT2AARBCL2L1MCL1 | |
| SCHEMBL8555123 | 0.87 | AR (0.51) | MEN1KMT2AARBCL2L1MCL1 | |
| SCHEMBL9025550 | 0.84 | AR (0.46) | ARBCL2L1MCL1PTGER4TDP1 | |
| SCHEMBL8556035 | 0.83 | MEN1 (0.45) | MEN1KMT2AARNR4A1NR4A2 | |
| SCHEMBL8555566 | 0.83 | CCR2 (0.41) | KMT2A | |
| SCHEMBL8555920 | 0.80 | PGR (0.46) | KMT2ATDP1GAATSHR | |
| SCHEMBL8559033 | 0.80 | GRM5 (0.44) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |