Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | PDE6D | O43924 | 1/20 | 0.42 |
| ▸ | PDE8A | O60658 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557830 | 0.87 | ADORA3 (0.43) | POLBHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL8554710 | 0.82 | POLB (0.50) | POLBHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL8554912 | 0.82 | PDE5A (0.64) | KDM4EALDH1A1MAPTMAPK1NPSR1 | |
| SCHEMBL8555929 | 0.81 | POLB (0.46) | POLBHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL9052411 | 0.76 | POLB (0.55) | POLBHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL8557495 | 0.76 | POLB (0.44) | POLBHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL8553821 | 0.76 | POLB (0.49) | POLBHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL8553393 | 0.74 | PDE2A (0.49) | POLBHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL8034425 | 0.71 | ADORA3 (0.61) | POLBHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL8557227 | 0.70 | ADORA3 (0.54) | POLBHPGDKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |