Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | PDE6D | O43924 | 1/20 | 0.49 |
| ▸ | PDE8A | O60658 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | PDE9A | O76083 | 1/20 | 0.49 |
| ▸ | PDE8B | O95263 | 1/20 | 0.49 |
| ▸ | PDE6A | P16499 | 1/20 | 0.49 |
| ▸ | PDE6G | P18545 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE6B | P35913 | 1/20 | 0.49 |
| ▸ | PDE6C | P51160 | 1/20 | 0.49 |
| ▸ | PDE1A | P54750 | 1/20 | 0.49 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557983 | 0.84 | DAO (0.43) | KDM4EALDH1A1HPGDADORA3ADORA1 | |
| SCHEMBL8558719 | 0.82 | ADORA3 (0.50) | PDE5APDE9AADORA3ADORA1 | |
| SCHEMBL9052411 | 0.81 | POLB (0.55) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL8557784 | 0.79 | PDE5A (0.47) | PDE2APDE5APDE9AALDH1A1MAPT | |
| SCHEMBL8034425 | 0.79 | ADORA3 (0.61) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL8554710 | 0.77 | POLB (0.50) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL8553821 | 0.75 | POLB (0.49) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL8555929 | 0.75 | POLB (0.46) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL8557227 | 0.74 | ADORA3 (0.54) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL8555643 | 0.74 | POLB (0.47) | PDE2APDE6DPDE8APDE5APDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |