Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556345 | 0.89 | ALDH1A1 (0.43) | MAPTALDH1A1HPGDTSHRTDP1 | |
| SCHEMBL8555047 | 0.89 | ALDH1A1 (0.43) | MAPTALDH1A1HPGDTSHRTDP1 | |
| SCHEMBL8556257 | 0.88 | MAPT (0.46) | MAPTALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL8558352 | 0.87 | MAPT (0.42) | MAPTALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL8553814 | 0.87 | MAPT (0.45) | MAPTALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL8556636 | 0.86 | MAPT (0.44) | MAPTALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL8559341 | 0.86 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2HPGDTDP1 | |
| SCHEMBL8556830 | 0.86 | ALDH1A1 (0.42) | MAPTALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL8555536 | 0.86 | ALDH1A1 (0.42) | MAPTALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL8559800 | 0.85 | SLC40A1 (0.45) | MAPTALDH1A1SMN1; SMN2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |