Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556345 | 0.90 | ALDH1A1 (0.43) | MAPTALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL8559918 | 0.90 | MAPT (0.41) | MAPTALDH1A1TSHRRXFP1KDM4E | |
| SCHEMBL8553814 | 0.88 | MAPT (0.45) | MAPTALDH1A1TSHRRXFP1KDM4E | |
| SCHEMBL8561140 | 0.88 | MAPT (0.41) | MAPTALDH1A1TSHRRXFP1KDM4E | |
| SCHEMBL8554227 | 0.87 | CCNT1 (0.49) | MAPTALDH1A1CCNT1CDK9PIK3CD | |
| SCHEMBL8555761 | 0.87 | MAPT (0.46) | MAPTALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL8561427 | 0.86 | ALDH1A1 (0.42) | MAPTALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL8559711 | 0.84 | MAPT (0.47) | MAPTALDH1A1TSHRKDM4ECCNT1 | |
| SCHEMBL8555047 | 0.83 | ALDH1A1 (0.43) | MAPTALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL8559708 | 0.83 | MAPT (0.46) | MAPTALDH1A1RXFP1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |