Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NAT1 | P18440 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555536 | 0.90 | ALDH1A1 (0.42) | MAPTALDH1A1NAT1KDM4ERXFP1 | |
| SCHEMBL8558700 | 0.89 | PGR (0.46) | MAPTALDH1A1KDM4ERXFP1NPSR1 | |
| SCHEMBL8561447 | 0.89 | FBP1 (0.45) | MAPTALDH1A1KDM4ERXFP1NPSR1 | |
| SCHEMBL8560392 | 0.88 | MAPT (0.44) | MAPTALDH1A1KDM4ERXFP1NPSR1 | |
| SCHEMBL8553792 | 0.88 | MAPT (0.40) | MAPTALDH1A1NAT1KDM4ERXFP1 | |
| SCHEMBL8556712 | 0.87 | MAPT (0.42) | MAPTALDH1A1KDM4ERXFP1NPSR1 | |
| SCHEMBL8556636 | 0.86 | MAPT (0.44) | MAPTALDH1A1KDM4ERXFP1NPSR1 | |
| SCHEMBL8555761 | 0.86 | MAPT (0.46) | MAPTALDH1A1KDM4ENPSR1LMNA | |
| SCHEMBL8555293 | 0.85 | PIK3CG (0.43) | MAPTALDH1A1KDM4ELMNAPGR | |
| SCHEMBL8557471 | 0.84 | MAPT (0.48) | MAPTALDH1A1KDM4ERXFP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |