Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | STK17B | O94768 | 1/20 | 0.46 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.46 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.46 |
| ▸ | DAPK2 | Q9UIK4 | 1/20 | 0.46 |
| ▸ | GNRHR | P30968 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977603 | 0.91 | HDAC1 (0.47) | DAPK3STK17BDAPK1STK17ADAPK2 | |
| SCHEMBL7899429 | 0.73 | GNRHR (0.41) | GNRHR | |
| SCHEMBL6983626 | 0.72 | HDAC1 (0.48) | GNRHR | |
| SCHEMBL7912488 | 0.70 | GNRHR (0.42) | GNRHR | |
| SCHEMBL8700278 | 0.70 | DAPK3 (0.44) | DAPK3STK17BDAPK1STK17ADAPK2 | |
| SCHEMBL6982755 | 0.70 | HDAC1 (0.42) | GNRHR | |
| SCHEMBL6978805 | 0.69 | HDAC1 (0.45) | GNRHR | |
| SCHEMBL8596661 | 0.68 | HTR1F (0.42) | — | |
| SCHEMBL7907194 | 0.68 | GNRHR (0.60) | GNRHR | |
| SCHEMBL19308465 | 0.67 | P2RY12 (0.73) | DAPK3STK17BDAPK1STK17ADAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873336-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (a New Jersey corp.) (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997021704-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1997-06-19 | — | — | WO | disclosed |