Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551342 | 0.86 | LMNA (0.54) | KMT2APKMLMNAKDM4ETSHR | |
| SCHEMBL7963149 | 0.78 | GAA (0.43) | KMT2AGAALMNAKDM4ETSHR | |
| SCHEMBL7963151 | 0.78 | GAA (0.43) | KMT2AGAALMNAKDM4ETSHR | |
| SCHEMBL5184903 | 0.75 | KMT2A (0.69) | KMT2AGAALMNATSHRALDH1A1 | |
| SCHEMBL8694256 | 0.75 | NPC1 (0.53) | KMT2AGAALMNATSHRL3MBTL1 | |
| SCHEMBL17785271 | 0.75 | GLA (0.47) | KMT2AGAALMNAKDM4ETSHR | |
| SCHEMBL6320216 | 0.72 | ALDH1A1 (0.44) | KMT2APKMLMNAKDM4ETSHR | |
| SCHEMBL6465694 | 0.72 | LMNA (0.55) | KMT2APKMLMNAKDM4ETSHR | |
| SCHEMBL20981704 | 0.72 | LMNA (0.73) | KMT2AGAALMNAKDM4ETSHR | |
| SCHEMBL8551669 | 0.72 | HTT (0.68) | KMT2AGAALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |