Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | FPR1 | P21462 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553023 | 0.88 | FPR1 (0.57) | HTTRAB9AALDH1A1NPSR1FPR1 | |
| SCHEMBL8699832 | 0.81 | ALDH1A1 (0.73) | HTTRAB9AALDH1A1NPSR1KDM4E | |
| SCHEMBL8696284 | 0.79 | ALDH1A1 (0.72) | HTTRAB9AALDH1A1NPSR1KDM4E | |
| SCHEMBL8554553 | 0.79 | PTGS2 (0.66) | FPR1LMNAGAA | |
| SCHEMBL13975009 | 0.79 | ALDH1A1 (0.77) | HTTRAB9AALDH1A1NPSR1KDM4E | |
| SCHEMBL3516960 | 0.77 | ALDH1A1 (0.74) | HTTRAB9AALDH1A1NPSR1KDM4E | |
| SCHEMBL7934013 | 0.77 | ALDH1A1 (0.79) | HTTRAB9AALDH1A1NPSR1KDM4E | |
| SCHEMBL4158508 | 0.77 | ALDH1A1 (0.79) | HTTRAB9AALDH1A1NPSR1KDM4E | |
| SCHEMBL9010473 | 0.77 | ALDH1A1 (0.79) | HTTRAB9AALDH1A1NPSR1KDM4E | |
| SCHEMBL8553556 | 0.76 | CYP2C9 (0.70) | ALDH1A1NPSR1KDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |