Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772397 | 0.86 | ALDH1A1 (0.54) | HCAR2ALDH1A1LMNAESR1TSHR | |
| SCHEMBL28699965 | 0.85 | — | — | |
| SCHEMBL11030932 | 0.83 | — | — | |
| SCHEMBL2400945 | 0.81 | NAAA (0.53) | HCAR2ALDH1A1LMNAESR1TSHR | |
| SCHEMBL1203240 | 0.79 | ALOX15 (0.50) | HCAR2ALDH1A1LMNATSHRALOX15 | |
| SCHEMBL2540116 | 0.77 | — | — | |
| SCHEMBL12522481 | 0.77 | CHRNB2 (0.44) | HCAR2ALDH1A1CHRM1CHRNB2CHRNA4 | |
| Methylhydrazine SCHEMBL11031292 | 0.76 | ALDH1A1 (0.37) | HCAR2ALDH1A1CHRM1CHRNB2CHRNA4 | |
| SCHEMBL30532490 | 0.76 | ALDH1A1 (0.48) | HCAR2ALDH1A1LMNAESR1TSHR | |
| SCHEMBL8909513 | 0.75 | MEN1 (0.45) | HCAR2ALDH1A1CHRM1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519083-B1 | PROCESS FOR PRODUCING HEXAHYDROPYRIDAZINE-1,2-DICARBOXYLIC ACID DERIVATIVES | IHARA CHEMICAL IND CO (JP) | 1998-09-16 | — | — | EP | disclosed |
| US-5310738-A | From a dicarboxyhydrazine and dihalobutane | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0519083-A1 | PROCESS FOR PRODUCING HEXAHYDROPYRIDAZINE-1,2-DICARBOXYLIC ACID DERIVATIVE | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |