Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561913 | 0.89 | AR (0.46) | MAPTLMNAGAAPOLBTSHR | |
| SCHEMBL8557604 | 0.89 | AR (0.51) | PGRGAAKDM1APOLBPTPN2 | |
| SCHEMBL8559033 | 0.88 | GRM5 (0.44) | PGRMAPTPTPN2PTPN1HTR1A | |
| SCHEMBL8558557 | 0.86 | MEN1 (0.48) | KMT2A | |
| SCHEMBL8559014 | 0.84 | MAPT (0.48) | PGRMAPTTP53LMNAGAA | |
| SCHEMBL9025550 | 0.83 | AR (0.46) | PGRMAPTLMNAGAAPOLB | |
| SCHEMBL8556135 | 0.82 | MAPT (0.48) | MAPTTP53LMNAGAAPOLB | |
| SCHEMBL8555123 | 0.82 | AR (0.51) | MAPTGAAPOLBPTPN2PTPN1 | |
| SCHEMBL8554235 | 0.80 | MEN1 (0.45) | GAATSHRKMT2ATDP1 | |
| SCHEMBL8556146 | 0.80 | PGR (0.50) | PGRMAPTTP53LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |