Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561913 | 0.89 | AR (0.46) | ARMAPT | |
| SCHEMBL8555123 | 0.89 | AR (0.51) | PTPN1PTPN5PTPN2ARPIK3CD | |
| SCHEMBL8555920 | 0.88 | PGR (0.46) | PTPN1PGRPTPN2PIK3CDPIK3CA | |
| SCHEMBL8558557 | 0.86 | MEN1 (0.48) | KAT6A | |
| SCHEMBL8556744 | 0.84 | GRM5 (0.44) | GRM5PTPN1PTPN5PGRADAMTS4 | |
| SCHEMBL9025550 | 0.83 | AR (0.46) | PGRARMAPT | |
| SCHEMBL9026048 | 0.82 | MEN1 (0.50) | GRM5PTPN1ARKAT6A | |
| SCHEMBL8558438 | 0.82 | HPGD (0.41) | GRM5PTPN1PTPN5PTPN2MAPT | |
| SCHEMBL8557604 | 0.82 | AR (0.51) | PTPN1PTPN5PGRPTPN2AR | |
| SCHEMBL8554235 | 0.80 | MEN1 (0.45) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |