Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.36 |
| ▸ | NMT1 | P30419 | 4/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557719 | 0.90 | CHRM1 (0.34) | ITGB3ITGA2BNMT1ITGAVCHRM2 | |
| SCHEMBL8555786 | 0.79 | ITGB3 (0.44) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL25541391 | 0.79 | LMNA (0.33) | ITGB3ITGA2BSLC6A4 | |
| SCHEMBL7885967 | 0.77 | ITGB3 (0.41) | ITGB3ITGA2BNMT1ITGAVCHRM2 | |
| Hydrochloric Acid SCHEMBL1906833 | 0.75 | ITGB3 (0.40) | ITGB3ITGA2BNMT1ITGAVCHRM2 | |
| SCHEMBL24008981 | 0.74 | ITGB3 (0.36) | ITGB3ITGA2BNMT1ITGAVCHRM2 | |
| SCHEMBL6618139 | 0.73 | LMNA (0.43) | ITGB3ITGA2BCHRM1CHRM3GNAO1 | |
| SCHEMBL12308362 | 0.72 | GNAO1 (0.39) | ITGB3ITGA2BSLC6A4GNAO1HRH3 | |
| SCHEMBL8555124 | 0.72 | CHRM1 (0.35) | ITGB3ITGA2BNMT1ITGAVCHRM2 | |
| SCHEMBL23945815 | 0.71 | GNAO1 (0.38) | ITGB3ITGA2BNMT1SLC6A4GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |