SCHEMBL855646

SCHEMBL855646

O=C1OC(=O)c2c(Br)ccc(Br)c21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
ALOX15 P16050 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 3/20 0.40
POLB P06746 3/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
HTT P42858 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CA1 P00915 2/20 0.35
CA9 Q16790 2/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
HSP90AA1 P07900 1/20 0.35
TLR9 Q9NR96 1/20 0.35
TYMS P04818 1/20 0.33
PARP1 P09874 1/20 0.32
CYP1B1 Q16678 1/20 0.31
PTPRC P08575 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29688935 1.00 TSHR (0.52) TSHRALOX15TDP1MEN1POLB
SCHEMBL855199 0.86 TSHR (0.41) TSHRALOX15TDP1MEN1POLB
SCHEMBL1829004 0.81 KDM4E (0.50) TSHRTDP1MEN1POLBKMT2A
SCHEMBL29569862 0.78 ALOX15 (0.50) TSHRALOX15TDP1MEN1POLB
SCHEMBL550679 0.78 ALOX15 (0.50) TSHRALOX15TDP1MEN1POLB
SCHEMBL29462451 0.76 TSHR (0.46) TSHRALOX15TDP1MEN1POLB
SCHEMBL855919 0.76 TSHR (0.46) TSHRALOX15TDP1MEN1POLB
SCHEMBL16686944 0.74 CA9 (0.39) TSHRMEN1POLBKMT2AALDH1A1
SCHEMBL855214 0.74 TSHR (0.56) TSHRALDH1A1CA1CA2AHR
SCHEMBL322393 0.73 TYMS (0.62) ALOX15TDP1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117402494-A Complex high-strength polyarylene sulfide based composite material and preparation and application thereof 新凝合科技(成都)有限公司 2024-01-16 CN claimed
CN-113121410-B Organic circular polarization luminescent material and preparation method and application thereof 华南师范大学 2022-05-20 CN claimed
CN-113121410-A Organic circular polarization luminescent material and preparation method and application thereof 华南师范大学 2021-07-16 CN claimed
CN-108101831-B Aromatic amine compound containing tetramethyl isoindoline or oxide structure thereof and preparation method thereof 兰州大学 2021-06-04 CN claimed
CN-110724263-B Boron-containing two-dimensional polyarylene sulfide material with neutron absorption function and preparation method thereof 四川大学 2020-08-14 CN claimed
CN-110564154-B Bonded polyarylene sulfide metal composite material with nuclear radiation protection function and preparation method thereof 四川大学 2020-07-31 CN claimed
CN-110724263-A Boron-containing two-dimensional polyarylene sulfide material with neutron absorption function and preparation method thereof 四川大学 2020-01-24 CN claimed
CN-110698858-A High boronizing activity polyarylene sulfide composite material with nuclear radiation protection function and preparation thereof 四川大学 2020-01-17 CN claimed
CN-110564154-A bonded polyarylene sulfide metal composite material with nuclear radiation protection function and preparation method thereof 四川大学 2019-12-13 CN claimed
JP-11323029-A None JP disclosed
CN-117402494-A Complex high-strength polyarylene sulfide based composite material and preparation and application thereof 新凝合科技(成都)有限公司 2024-01-16 CN disclosed
US-20230323137-A1 COMPOSITION FOR SEALING COATED ELECTRIC WIRE, AND COATED ELECTRIC WIRE TOAGOSEI CO. LTD. (JP) 2023-10-12 US disclosed
CN-113121410-B Organic circular polarization luminescent material and preparation method and application thereof 华南师范大学 2022-05-20 CN disclosed
CN-113121410-A Organic circular polarization luminescent material and preparation method and application thereof 华南师范大学 2021-07-16 CN disclosed
US-4404361-A BISIMIDE CONTAINING HALOGEN ATOMS AND AMMONIUM ACID TETRAHALOPHTHALATE SAYTECH, INC. (US) 1983-09-13 US disclosed
US-4401778-A HALOGENATED IMIDE-CONTAINING POLYOLS SAYTECH, INC. (US) 1983-08-30 US disclosed
EP-0026749-A1 Phthalimidine derivatives and pharmaceutical compositions containing them Astra Läkemedel Aktiebolag (SE) 1981-04-08 EP disclosed
US-4250007-A Photocurable acrylic phosphate esters of epoxidized polybutadiene UBE INDUSTRIES, LTD. (JP) 1981-02-10 US disclosed
US-4132721-A Optically active anthracyclinones and process therefor SOCIETA FARMACEUTICI ITALIA S.P.A. (IT) 1979-01-02 US disclosed
US-3974109-A FLAME RETARDANT FOAMS UNION CARBIDE CORPORATION (US) 1976-08-10 US disclosed