Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530550 | 0.80 | RAB9A (0.58) | RAB9ANPC1KLF5LMNASMN1; SMN2 | |
| SCHEMBL5532731 | 0.80 | NPC1 (0.54) | RAB9ANPC1KLF5LMNASMN1; SMN2 | |
| SCHEMBL5515761 | 0.77 | RAB9A (0.48) | RAB9ANPC1KLF5LMNASMN1; SMN2 | |
| SCHEMBL5517429 | 0.72 | RAB9A (0.46) | RAB9ANPC1KLF5LMNASMN1; SMN2 | |
| SCHEMBL8558701 | 0.71 | LMNA (0.43) | RAB9ANPC1KLF5LMNASMN1; SMN2 | |
| SCHEMBL9427792 | 0.70 | MLKL (0.53) | RAB9ANPC1KLF5LMNASMN1; SMN2 | |
| SCHEMBL5443699 | 0.69 | PPARA (0.48) | RAB9ANPC1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL27447670 | 0.69 | ELANE (0.45) | RAB9ANPC1L3MBTL1PKMKMT2A | |
| SCHEMBL8557020 | 0.68 | GPBAR1 (0.46) | RAB9ANPC1SMN1; SMN2KMT2ANFKB1 | |
| SCHEMBL7596328 | 0.68 | KMT2A (0.47) | RAB9ANPC1KLF5LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |