Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.36 |
| ▸ | F2R | P25116 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CPN1 | P15169 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556638 | 0.91 | TPSAB1 (0.41) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL16944211 | 0.88 | MAPT (0.40) | MEN1MAPTKMT2AATMEPHX2 | |
| SCHEMBL29136168 | 0.85 | MEN1 (0.48) | MEN1MAPTKMT2AATMALDH1A1 | |
| SCHEMBL27295498 | 0.83 | SLC6A1 (0.38) | GNAI3GNAO1GNAI1ALDH1A1CPN1 | |
| SCHEMBL3597232 | 0.81 | TDP1 (0.44) | HTR4GNAI3GNAO1GNAI1ITGB3 | |
| Hydrochloric Acid SCHEMBL2942254 | 0.80 | GNAI3 (0.44) | HTR4GNAI3GNAO1GNAI1ITGB3 | |
| SCHEMBL8556452 | 0.79 | GNAI3 (0.43) | HTR4GNAI3GNAO1GNAI1ITGB3 | |
| SCHEMBL380886 | 0.78 | TSHR (0.44) | HTR4GNAI3GNAO1GNAI1ITGB3 | |
| SCHEMBL8162908 | 0.76 | GNAO1 (0.48) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL13106122 | 0.76 | GNAI3 (0.39) | HTR4GNAI3GNAO1GNAI1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |